Saccharide Isomerate in Hautpflege

Saccharide Isomerate In Skincare

Saccharide Isomerate is a powerful humectant derived from plant sugars that strengthens the skin's natural moisture barrier and provides long-lasting hydration. This active ingredient attracts and retains moisture in the skin, resulting in softer, smoother skin and restoring the skin barrier.

Saccharide Isomerate Overview

  • Origin: Derived through isomerization of plant-based D-glucose, mainly from corn or sugarcane.
  • Effect on the Skin: Provides instant hydration that lasts up to 72 hours, relieves itchy, flaky, and dry skin, and strengthens the natural skin barrier.
  • Ideal for: Especially suitable for dry, sensitive skin and skin with weakened barrier function, such as eczema.
  • Interesting Fact: Saccharide Isomerate has a natural affinity to the skin because it resembles the carbohydrates in the skin's natural moisturizing factor (NMF).
  • Other Names: Often also known as Pentavitin.

The Effects of Saccharide Isomerate

Saccharide Isomerate works in several important areas of skincare:

  • Hydration: It deeply binds moisture in the skin, providing long-lasting hydration that lasts up to 72 hours.
  • Barrier Function: It strengthens the skin barrier by promoting the expression of proteins such as hyaluron synthase-3 and loricrin, which are crucial for skin integrity.
  • Protection Against Environmental Factors: By strengthening the skin barrier, it makes the skin more resistant to environmental aggressors such as pollution and UV radiation.
  • Itching and Dryness: It alleviates itchy and flaky skin, making it ideal for caring for dry and sensitive skin.

How To Use of Saccharide Isomerate

  • Frequency of Use: Can be used daily, ideally twice a day for optimal results.
  • Concentration: Studies have shown that concentrations ranging from 0.6% to 3% are effective and safe.
  • Combination: It pairs well with other moisturizing ingredients such as hyaluronic acid and ceramides to enhance moisturizing and protective properties.

What is Saccharide Isomerate?

Chemically, Saccharide Isomerate is a mixture of various sugars, mainly glucose and fructose, resulting from the isomerization of plant sugar. It also contains other sugars such as rhamnose, galactose, and N-acetylglucosamine. This composition gives it a strong affinity to the skin, enabling it to effectively bind moisture and strengthen the skin barrier.


  1. Rastogi, Rachna. "The Skin-Like Moisturiser." COSSMA, 2023.
  2. "Safety Assessment of Anhydrogalactose, Anhydroglucitol, Anhydroxylitol, Arabinose, Psicose, Saccharide Hydrolysate, and Saccharide Isomerate as Used in Cosmetics." Cosmetic Ingredient Review, 2020.
  3. Hartini, Helen et al. "The Effect of a Moisturizing Cream Containing Saccharide Isomerate and Ceramide on Reducing Transepidermal Water Loss in Eczema." International Conference on Health Informatics and Medical Application Technology, 2019.

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